Chrome Default Profile

You can adjust registry settings so that Chrome starts with a specific user profile. To begin, open regedit and navigate to HKEY_CLASSES_ROOT\ChromeHTML\shell\open\command

Modify value of Default key

Original

"C:\Program Files\Google\Chrome\Application\chrome.exe" --single-argument %1

After my changes

"C:\Program Files\Google\Chrome\Application\chrome.exe" --profile-directory="Default" --single-argument %1

Note, in the example above, I am not passing the full file path to the profile folder, instead I simply list the profile specific folder name.

Reference: https://superuser.com/questions/109589/make-google-chrome-with-specific-user-profile-as-default-browser

Start Chrome with specific user profile

Running chrome.exe from CMD will fail so be sure to include it in the $PATH variable
C:\Program Files\Google\Chrome\Application

chrome.exe --args --profile-directory=Default

You can find the profiles located in the user home directory
%USERPROFILE%\AppData\Local\\Google\Chrome\User Data\

As you can see, I have a few profiles to choose from. Once I know which one to use, I will supply the directory name to the –profile-directory option.

chrome.exe --args --profile-directory="Profile 3"

In my situation I selected the Default profile that was signed in the with the specific Google account I had need to work with.

chrome.exe --args --profile-directory="Profile 3"